The Chameleon Men were a group of shapeshifting aliens who knocked out and replaced the Legion of Super-Heroes during Supergirl's visit from 1962. They then locked Supergirl and Whizzy in the Phantom Zone. However, Supergirl and Whizzy escaped and imprisoned them. ("Supergirl's Greatest Challenge!")
- Due to their similar abilities, and the term "Chameleon Men", these may be an early form of, or a precursor to, the Durlans, the race to which Chameleon Man is a member.