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Brainiac 2, aka Vril Dox 2, is a Coluan man, who became Brainiac's adoptive son. He appears in silver age continuity. In modern-age continuity, he's Brainiac's biological son. In both continuities he rebelled against the Computer Tyrants and against his father, fighting for the freedom of Colu.
Brainiac 5 descended from him. On multiple occasions, Brainiac 5 has sent projections of himself back in time to interact with his ancestor.